Clinical efficacy and safety of 20% glycolic peel, 15% lactic peel, and topical 20% vitamin C in constitutional type of periorbital melanosis: a comparative study.
randomized
EVIDENCE COMPARISON
SupportiveVitamin C (L-Ascorbic Acid)
vs Glycolic Acid
for Pigmentation Reduction
Limited evidence suggests vitamin C reduces pigmentation nearly three times more effectively than glycolic acid for improving skin tone.
2.75x
Effect ratio
Vitamin C (L-Ascorbic Acid)
Favored
1
Study
Direct
Comparison
CoreSubjective endpointTone
Limits: Includes subjective endpoint
How to read this claim
Direct comparison with enough study context for public-facing comparative wording, with limits noted for includes subjective endpoint.
The published evidence does not currently show a major generalization warning beyond the listed study limits.