Comparison of the clinical efficacy of topical tretinoin 0.05% cream and tacrolimus 0.1% ointment plus iontophoresis in the management of palmoplantar psoriasis.
randomized
EVIDENCE COMPARISON
SupportiveTacrolimus
vs Tretinoin
for Redness Reduction
Limited evidence suggests tacrolimus may reduce redness slightly more than tretinoin for improving skin tone.
1.06x
Effect ratio
Tacrolimus
Favored
1
Study
Direct
Comparison
CoreSubjective endpointTone
Limits: Includes subjective endpoint
How to read this claim
Direct comparison with enough study context for public-facing comparative wording, with limits noted for includes subjective endpoint.
The published evidence does not currently show a major generalization warning beyond the listed study limits.