Single-blind, randomized controlled trial evaluating the treatment of facial seborrheic dermatitis with hydrocortisone 1% ointment compared with tacrolimus 0.1% ointment in adults.
randomized
EVIDENCE COMPARISON
DirectionalTacrolimus
vs Sertaconazole
for Redness Reduction
Early or indirect evidence suggests tacrolimus may reduce redness 8% more effectively than sertaconazole for improving skin tone, based on indirect comparison.
1.08x
Effect ratio
Tacrolimus
Favored
2
Studies
Indirect
Comparison
ExploratorySubjective endpointTone
Limits: Indirect comparison · Includes subjective endpoint · Early-stage evidence tier
This is an indirect comparison — the two ingredients were not tested head-to-head in the same trial. The ratio is derived from separate studies against a common comparator.
How to read this claim
Kept public as exploratory because it indirect comparison; includes subjective endpoint; early-stage evidence tier.
Some study-specific context may affect how broadly this comparison generalizes.