2% supramolecular salicylic acid hydrogel vs. adapaline gel in mild to moderate acne vulgaris treatment: A multicenter, randomized, evaluator-blind, parallel-controlled trial.
randomized
EVIDENCE COMPARISON
SupportiveSalicylic Acid
vs Adapalene
for Surface Smoothness
Limited evidence suggests salicylic acid and adapalene perform equally for improving skin surface smoothness and texture.
1.00x
Effect ratio
Neither
Favored
1
Study
Direct
Comparison
CoreSubjective endpointTexture
Limits: Includes subjective endpoint
How to read this claim
Direct comparison with enough study context for public-facing comparative wording, with limits noted for includes subjective endpoint.
The published evidence does not currently show a major generalization warning beyond the listed study limits.