EVIDENCE COMPARISON

Gold Standard

Retinol
vs Tretinoin
for Surface Smoothness

Studies show retinol improved skin surface smoothness 1.09 times more than tretinoin for texture enhancement.

1.09x

Effect ratio

Retinol

Favored

2

Studies

Direct

Comparison

Texture

How to read this claim

Direct comparison with enough study context for public-facing comparative wording, with limits noted for mixed endpoint quality.

The published evidence does not currently show a major generalization warning beyond the listed study limits.

1 linked trialIngredient trial

Source Studies (2)

Combination Superficial Peels With Salicylic Acid and Post-Peel Retinoids.

double-blind, split-face

A Randomized, Double-blind, Split-face Study Comparing the Efficacy and Tolerability of Three Retinol-based Products vs. Three Tretinoin-based Products in Subjects With Moderate to Severe Facial Photodamage.

randomized, double-blind, split-face
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