EVIDENCE COMPARISON

Supportive

Petrolatum
vs Ceramides
for Barrier Integrity

Limited evidence suggests petrolatum provides 1.53 times better barrier integrity for skin moisture compared to ceramides in direct comparison.

1.53x

Effect ratio

Petrolatum

Favored

1

Study

Direct

Comparison

CoreSubjective endpointMoisture

Limits: Includes subjective endpoint

How to read this claim

Direct comparison with enough study context for public-facing comparative wording, with limits noted for includes subjective endpoint.

The published evidence does not currently show a major generalization warning beyond the listed study limits.

Source Studies (1)

A Comparative, Multicenter, Prospective, Randomized Study to Evaluate the Efficacy, Safety, and Delay of Relapse of Ceramide-Based Post-biotic Moisturizer Versus Paraffin-Based Moisturizer in Mild to Moderate Atopic Dermatitis.

randomized
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