Permethrin 5% cream versus metronidazole 0.75% gel for the treatment of papulopustular rosacea. A randomized double-blind placebo-controlled study.
controlled
EVIDENCE COMPARISON
DirectionalPermethrin 5%
vs Metronidazole
for Redness Reduction
Early or indirect evidence suggests permethrin 5% and metronidazole show equal performance for reducing redness and improving skin tone.
1.00x
Effect ratio
Neither
Favored
1
Study
Direct
Comparison
ExploratorySubjective endpointTone
Limits: Includes subjective endpoint · Early-stage evidence tier
How to read this claim
Kept public as exploratory because it includes subjective endpoint; early-stage evidence tier.
Some study-specific context may affect how broadly this comparison generalizes.