Topical epidermal growth factor for the improvement of acne lesions: a randomized, double-blinded, placebo-controlled, split-face trial.
randomized, double-blind, split-face
EVIDENCE COMPARISON
DirectionalPanthenol
vs Epidermal Growth Factor (EGF)
for Hydration Retention
Early or indirect evidence suggests epidermal growth factor may provide over 4 times better hydration retention than panthenol for skin moisture, based on indirect comparison.
4.22x
Effect ratio
Epidermal Growth Factor (EGF)
Favored
2
Studies
Indirect
Comparison
ExploratoryMoisture
Limits: Indirect comparison · Early-stage evidence tier
This is an indirect comparison — the two ingredients were not tested head-to-head in the same trial. The ratio is derived from separate studies against a common comparator.
How to read this claim
Kept public as exploratory because it indirect comparison; early-stage evidence tier.
Some study-specific context may affect how broadly this comparison generalizes.