A double-blind study of I% metronidazole cream versus systemic oxytetracycline therapy for rosacea.
controlled
EVIDENCE COMPARISON
DirectionalEarly or indirect evidence suggests oxytetracycline and metronidazole show similar effectiveness for reducing redness and improving skin tone.
Effect ratio
Favored
Study
Comparison
Limits: Includes subjective endpoint · Early-stage evidence tier
Kept public as exploratory because it includes subjective endpoint; early-stage evidence tier.
Some study-specific context may affect how broadly this comparison generalizes.