Topical 5% tranexamic acid for the treatment of melasma in Asians: a double-blind randomized controlled clinical trial.
randomized, double-blind
EVIDENCE COMPARISON
Gold StandardEarly or indirect evidence suggests tranexamic acid provides 10% greater redness reduction compared to no treatment, improving skin tone evenness.
Effect ratio
Favored
Studies
Comparison
Tone
Kept public as exploratory because it includes estimated measurement.
Some study-specific context may affect how broadly this comparison generalizes.