Antiaging efficacy of melatonin-based day and night creams: A randomized, split-face, assessor-blinded proof-of-concept trial
randomized, split-face
EVIDENCE COMPARISON
StrongNo Skincare
vs Melatonin
for Wrinkle Reduction
Evidence suggests no skincare provides 18% better wrinkle reduction for firmness compared to melatonin-based creams.
1.18x
Effect ratio
No Skincare
Favored
1
Study
Direct
Comparison
CoreSubjective endpointFirmness
Limits: Includes subjective endpoint
How to read this claim
Direct comparison with enough study context for public-facing comparative wording, with limits noted for includes subjective endpoint.
The published evidence does not currently show a major generalization warning beyond the listed study limits.