EVIDENCE COMPARISON

Strong

No Skincare
vs Melatonin
for Surface Smoothness

Evidence suggests no skincare provides 1.36 times better surface smoothness for skin texture compared to melatonin-based creams.

1.36x

Effect ratio

No Skincare

Favored

1

Study

Direct

Comparison

CoreSubjective endpointTexture

Limits: Includes subjective endpoint

How to read this claim

Direct comparison with enough study context for public-facing comparative wording, with limits noted for includes subjective endpoint.

The published evidence does not currently show a major generalization warning beyond the listed study limits.

Source Studies (1)

Antiaging efficacy of melatonin-based day and night creams: A randomized, split-face, assessor-blinded proof-of-concept trial

randomized, split-face
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