Antiaging efficacy of melatonin-based day and night creams: A randomized, split-face, assessor-blinded proof-of-concept trial
randomized, split-face
EVIDENCE COMPARISON
StrongNo Skincare
vs Melatonin
for Hydration Retention
Evidence suggests no skincare provides 2.47 times better hydration retention for moisture compared to melatonin-based skincare products.
2.47x
Effect ratio
No Skincare
Favored
1
Study
Direct
Comparison
CoreSubjective endpointMoisture
Limits: Includes subjective endpoint
How to read this claim
Direct comparison with enough study context for public-facing comparative wording, with limits noted for includes subjective endpoint.
The published evidence does not currently show a major generalization warning beyond the listed study limits.