A Randomized, Double-Blind, Placebo-Controlled, Split-Face Study of the Efficacy of Topical Epidermal Growth Factor for the Treatment of Melasma.
randomized, double-blind, split-face
EVIDENCE COMPARISON
Gold StandardNo Skincare
vs Epidermal Growth Factor (EGF)
for Pigmentation Reduction
Studies show no skincare treatment reduced pigmentation 5.60 times more effectively than epidermal growth factor for improving skin tone.
5.60x
Effect ratio
No Skincare
Favored
1
Study
Direct
Comparison
Tone
How to read this claim
Direct comparison with enough study context for public-facing comparative wording, with limits noted for includes subjective endpoint.
The published evidence does not currently show a major generalization warning beyond the listed study limits.