Efficacy and safety of calcipotriol as a potential topical treatment of acne vulgaris: a randomized, controlled, triple blinded, split-face clinical trial
randomized, split-face
EVIDENCE COMPARISON
DirectionalNo Skincare
vs Clobetasol
for Tone Evenness
Early or indirect evidence suggests clobetasol improves tone evenness 1.82 times more than no skincare treatment, based on indirect comparison.
1.82x
Effect ratio
Clobetasol
Favored
2
Studies
Indirect
Comparison
ExploratorySubjective endpointTone
Limits: Indirect comparison · Includes subjective endpoint · Early-stage evidence tier
This is an indirect comparison — the two ingredients were not tested head-to-head in the same trial. The ratio is derived from separate studies against a common comparator.
How to read this claim
Kept public as exploratory because it indirect comparison; includes subjective endpoint; early-stage evidence tier.
Some study-specific context may affect how broadly this comparison generalizes.
Source Studies (2)
Efficacy of the combined excimer light and topical calcipotriol for acral vitiligo: a randomized double‐blind comparative study
randomized, double-blind, split-face