Metronidazole 0.75% gel vs. ketoconazole 2% cream in the treatment of facial seborrheic dermatitis: a randomized, double-blind study.
randomized, double-blind
EVIDENCE COMPARISON
DirectionalKetoconazole
vs Oxytetracycline
for Redness Reduction
Early or indirect evidence suggests ketoconazole may reduce redness 1.17 times more effectively than oxytetracycline for improving skin tone, based on indirect comparison.
1.17x
Effect ratio
Ketoconazole
Favored
2
Studies
Indirect
Comparison
ExploratorySubjective endpointTone
Limits: Indirect comparison · Includes subjective endpoint · Early-stage evidence tier
This is an indirect comparison — the two ingredients were not tested head-to-head in the same trial. The ratio is derived from separate studies against a common comparator.
How to read this claim
Kept public as exploratory because it indirect comparison; includes subjective endpoint; early-stage evidence tier.
Some study-specific context may affect how broadly this comparison generalizes.