EVIDENCE COMPARISON

Strong

Ketoconazole
vs Metronidazole
for Redness Reduction

Evidence suggests ketoconazole reduces facial redness 1.17 times more effectively than metronidazole for improving skin tone.

1.17x

Effect ratio

Ketoconazole

Favored

1

Study

Direct

Comparison

CoreSubjective endpointTone

Limits: Includes subjective endpoint

How to read this claim

Direct comparison with enough study context for public-facing comparative wording, with limits noted for includes subjective endpoint.

The published evidence does not currently show a major generalization warning beyond the listed study limits.

Source Studies (1)

Metronidazole 0.75% gel vs. ketoconazole 2% cream in the treatment of facial seborrheic dermatitis: a randomized, double-blind study.

randomized, double-blind
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