Metronidazole 0.75% gel vs. ketoconazole 2% cream in the treatment of facial seborrheic dermatitis: a randomized, double-blind study.
randomized, double-blind
EVIDENCE COMPARISON
StrongEvidence suggests ketoconazole reduces facial redness 1.17 times more effectively than metronidazole for improving skin tone.
Effect ratio
Favored
Study
Comparison
Limits: Includes subjective endpoint
Direct comparison with enough study context for public-facing comparative wording, with limits noted for includes subjective endpoint.
The published evidence does not currently show a major generalization warning beyond the listed study limits.