EVIDENCE COMPARISON

Directional

Ivermectin
vs Permethrin 5%
for Redness Reduction

Early or indirect evidence suggests ivermectin reduces redness more effectively than permethrin 5% for skin tone improvement, based on indirect comparison.

1.40x

Effect ratio

Ivermectin

Favored

2

Studies

Indirect

Comparison

ExploratorySubjective endpointTone

Limits: Includes subjective endpoint · Indirect comparison · Missing exact quote provenance · Abstract-only source · Estimated effect size · Directional evidence tier

This is an indirect comparison — the two ingredients were not tested head-to-head in the same trial. The ratio is derived from separate studies against a common comparator.

How to read this claim

Published as an exploratory public claim: direct comparison with exact provenance, but with limits noted for includes subjective endpoint, indirect comparison, missing exact quote provenance, abstract-only source, estimated effect size, directional evidence tier.

The underlying trial context suggests this comparison may not generalize cleanly beyond the specific tested formulations.

Upstream study enrichment was not enabled for this export, so formulation-specific trial context may be incomplete here.

Source Studies (2)

Dermoscopic Response Predictors in Papulopustular Rosacea Treated with Topical Ivermectin and Metronidazole: A Prospective Observational Comparative Study.

randomized

Permethrin 5% cream versus metronidazole 0.75% gel for the treatment of papulopustular rosacea. A randomized double-blind placebo-controlled study.

controlled
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