… a New Hyaluronic Acid Matrix Ingredient Improves Skin Brightness, Hydration, Smoothness, and Roughness: Results from a Randomized, Double-Blinded, Placebo …
randomized, double-blind
EVIDENCE COMPARISON
DirectionalHyaluronic Acid Matrix (HAm)
vs Trifarotene
for Surface Smoothness
Early or indirect evidence suggests trifarotene may improve skin texture smoothness about 3 times more than hyaluronic acid matrix, based on indirect comparison.
3.04x
Effect ratio
Trifarotene
Favored
2
Studies
Indirect
Comparison
This is an indirect comparison — the two ingredients were not tested head-to-head in the same trial. The ratio is derived from separate studies against a common comparator.
Texture
How to read this claim
Kept public as exploratory because it indirect comparison; includes estimated measurement; early-stage evidence tier.
Some study-specific context may affect how broadly this comparison generalizes.
Source Studies (2)
… double-blind, placebo-controlled clinical trial evaluating the efficacy of a novel combination of hyaluronic acid serum and antioxidant cream for rejuvenation of the …
randomized, double-blind