… a New Hyaluronic Acid Matrix Ingredient Improves Skin Brightness, Hydration, Smoothness, and Roughness: Results from a Randomized, Double-Blinded, Placebo …
randomized, double-blind
EVIDENCE COMPARISON
DirectionalEarly or indirect evidence suggests hyaluronic acid matrix and epidermal growth factor show similar redness reduction effects for skin tone, based on indirect comparison.
Effect ratio
Favored
Studies
Comparison
This is an indirect comparison — the two ingredients were not tested head-to-head in the same trial. The ratio is derived from separate studies against a common comparator.
Tone
Kept public as exploratory because it indirect comparison; mixed endpoint quality; early-stage evidence tier.
Some study-specific context may affect how broadly this comparison generalizes.