EVIDENCE COMPARISON

Directional

Hyaluronic Acid Matrix (HAm)
vs Epidermal Growth Factor (EGF)
for Hydration Retention

Early or indirect evidence suggests epidermal Growth Factor may provide 1.5 times better moisture hydration retention than Hyaluronic Acid Matrix, based on indirect comparison.

1.50x

Effect ratio

Epidermal Growth Factor (EGF)

Favored

2

Studies

Indirect

Comparison

This is an indirect comparison — the two ingredients were not tested head-to-head in the same trial. The ratio is derived from separate studies against a common comparator.

Moisture

How to read this claim

Kept public as exploratory because it indirect comparison; early-stage evidence tier.

Some study-specific context may affect how broadly this comparison generalizes.

Source Studies (2)

… a New Hyaluronic Acid Matrix Ingredient Improves Skin Brightness, Hydration, Smoothness, and Roughness: Results from a Randomized, Double-Blinded, Placebo …

randomized, double-blind

Topical epidermal growth factor for the improvement of acne lesions: a randomized, double-blinded, placebo-controlled, split-face trial.

randomized, double-blind, split-face
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