Comparison between 1% tretinoin peeling versus 70% glycolic acid peeling in the treatment of female patients with melasma.
randomized, double-blind
EVIDENCE COMPARISON
StrongGlycolic Acid
vs Tretinoin
for Pigmentation Reduction
Evidence suggests glycolic acid and tretinoin perform equally for improving skin tone through pigmentation reduction.
1.00x
Effect ratio
Neither
Favored
1
Study
Direct
Comparison
CoreSubjective endpointTone
Limits: Includes subjective endpoint
How to read this claim
Direct comparison with enough study context for public-facing comparative wording, with limits noted for includes subjective endpoint.
The published evidence does not currently show a major generalization warning beyond the listed study limits.