Topical epidermal growth factor for the improvement of acne lesions: a randomized, double-blinded, placebo-controlled, split-face trial.
randomized, double-blind, split-face
EVIDENCE COMPARISON
SupportiveEpidermal Growth Factor (EGF)
vs Trifarotene
for Redness Reduction
Early or indirect evidence suggests trifarotene reduces skin redness 2.11 times more effectively than epidermal growth factor for improving skin tone, based on indirect comparison.
2.11x
Effect ratio
Trifarotene
Favored
1
Study
Indirect
Comparison
This is an indirect comparison — the two ingredients were not tested head-to-head in the same trial. The ratio is derived from separate studies against a common comparator.
Tone
How to read this claim
Kept public as exploratory because it indirect comparison; includes subjective endpoint.
Some study-specific context may affect how broadly this comparison generalizes.