Topical epidermal growth factor for the improvement of acne lesions: a randomized, double-blinded, placebo-controlled, split-face trial.
randomized, double-blind, split-face
EVIDENCE COMPARISON
SupportiveEpidermal Growth Factor (EGF)
vs Oxymetazoline Hydrochloride
for Redness Reduction
Early or indirect evidence suggests epidermal growth factor may reduce skin redness 4.5 times more effectively than oxymetazoline hydrochloride for improving tone, based on indirect comparison.
4.49x
Effect ratio
Epidermal Growth Factor (EGF)
Favored
2
Studies
Indirect
Comparison
This is an indirect comparison — the two ingredients were not tested head-to-head in the same trial. The ratio is derived from separate studies against a common comparator.
Tone
How to read this claim
Kept public as exploratory because it indirect comparison; mixed endpoint quality.
Some study-specific context may affect how broadly this comparison generalizes.
Source Studies (2)
41496 The Role of Topical Nasal Decongestant Oxymetazoline as a Novel Therapeutic Option for Post-Acne Erythema: A Split-Face, Double-Blind, Randomized …
randomized, double-blind, split-face