A randomized, controlled, split-face, double-blind comparison of a multimodality pigment-correcting serum containing lotus sprout extract versus hydroquinone for …
randomized, double-blind, split-face
EVIDENCE COMPARISON
DirectionalClobetasol
vs Lotus Sprout Extract
for Pigmentation Reduction
Early or indirect evidence suggests clobetasol and lotus sprout extract show similar pigmentation reduction effects for improving skin tone, based on indirect comparison.
1.00x
Effect ratio
Neither
Favored
2
Studies
Indirect
Comparison
ExploratorySubjective endpointTone
Limits: Indirect comparison · Includes subjective endpoint · Early-stage evidence tier
This is an indirect comparison — the two ingredients were not tested head-to-head in the same trial. The ratio is derived from separate studies against a common comparator.
How to read this claim
Kept public as exploratory because it indirect comparison; includes subjective endpoint; early-stage evidence tier.
Some study-specific context may affect how broadly this comparison generalizes.