Efficacy and safety of calcipotriol as a potential topical treatment of acne vulgaris: a randomized, controlled, triple blinded, split-face clinical trial
randomized, split-face
EVIDENCE COMPARISON
StrongEvidence suggests calcipotriol improves skin texture through pore refinement 1.5 times more effectively than trifarotene.
Effect ratio
Favored
Study
Comparison
Texture
Direct comparison with enough study context for public-facing comparative wording, with limits noted for includes subjective endpoint.
The published evidence does not currently show a major generalization warning beyond the listed study limits.