Efficacy and safety of calcipotriol as a potential topical treatment of acne vulgaris: a randomized, controlled, triple blinded, split-face clinical trial
randomized, split-face
EVIDENCE COMPARISON
StrongEvidence suggests calcipotriol may reduce redness twice as effectively as no treatment for improving skin tone.
Effect ratio
Favored
Study
Comparison
Tone
Direct comparison with enough study context for public-facing comparative wording, with limits noted for includes subjective endpoint.
The published evidence does not currently show a major generalization warning beyond the listed study limits.