Topical epidermal growth factor for the improvement of acne lesions: a randomized, double-blinded, placebo-controlled, split-face trial.
randomized, double-blind, split-face
EVIDENCE COMPARISON
DirectionalCalcipotriol (Vitamin D Analogue)
vs Epidermal Growth Factor (EGF)
for Pore Refinement
Early or indirect evidence suggests calcipotriol may improve skin texture through pore refinement 2.5 times more effectively than epidermal growth factor, based on indirect comparison.
2.51x
Effect ratio
Calcipotriol (Vitamin D Analogue)
Favored
2
Studies
Indirect
Comparison
This is an indirect comparison — the two ingredients were not tested head-to-head in the same trial. The ratio is derived from separate studies against a common comparator.
Texture
How to read this claim
Kept public as exploratory because it indirect comparison; includes subjective endpoint; early-stage evidence tier.
Some study-specific context may affect how broadly this comparison generalizes.
Source Studies (2)
Efficacy and safety of calcipotriol as a potential topical treatment of acne vulgaris: a randomized, controlled, triple blinded, split-face clinical trial
randomized, split-face