EVIDENCE COMPARISON

Gold Standard

Calcipotriol (Vitamin D Analogue)
vs Clobetasol
for Tone Evenness

Studies show calcipotriol improves tone evenness 10% more than clobetasol for achieving even skin tone.

1.10x

Effect ratio

Calcipotriol (Vitamin D Analogue)

Favored

1

Study

Direct

Comparison

CoreSubjective endpointTone

Limits: Includes subjective endpoint

How to read this claim

Direct comparison with enough study context for public-facing comparative wording, with limits noted for includes subjective endpoint.

The published evidence does not currently show a major generalization warning beyond the listed study limits.

Source Studies (1)

Efficacy of the combined excimer light and topical calcipotriol for acral vitiligo: a randomized double‐blind comparative study

randomized, double-blind, split-face
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