Topical epidermal growth factor for the improvement of acne lesions: a randomized, double-blinded, placebo-controlled, split-face trial.
randomized, double-blind, split-face
EVIDENCE COMPARISON
SupportiveEarly or indirect evidence suggests epidermal growth factor improves oil balance 1.5 times more than alpha-hydroxy acids for skin moisture, based on indirect comparison.
Effect ratio
Favored
Studies
Comparison
This is an indirect comparison — the two ingredients were not tested head-to-head in the same trial. The ratio is derived from separate studies against a common comparator.
Moisture
Kept public as exploratory because it indirect comparison.
Some study-specific context may affect how broadly this comparison generalizes.